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Albumin

Albumin is the most common protein in your blood that retains fluid and transports substances through your body.

What is Albumin?

Albumin is the most common protein in your blood, and your liver makes almost all of it. It does two main jobs: it keeps fluid inside your blood vessels instead of letting it leak into surrounding tissue, and it acts as a transport vehicle — carrying hormones, fatty acids, calcium and medications to where your body needs them. Because your liver produces it, albumin gives a broad read on how well your liver is working, how well-nourished you are, and whether you're well hydrated. It also dips temporarily during inflammation or illness, when your body shifts its protein-making to other priorities. That's why albumin tells you the most when you read it alongside your other markers, rather than on its own.

Why is Albumin relevant?

Albumin tells you two things at once: how well your liver is functioning and how good your nutritional status is. A healthy value means your liver is doing its job and your body has enough protein in reserve — for recovery, for transporting nutrients, and for repairing tissue. It's especially relevant if you train a lot, are recovering from surgery, or pay close attention to your protein intake. It also helps make sense of your other results: because albumin carries calcium in the blood, a low albumin can make your calcium level look artificially low — which is why we also measure corrected calcium.

Albumin high or low — what it means

A low albumin usually points to one of three things: your liver producing less of it, your body using up or losing protein faster than you take it in, or a period of inflammation lowering it temporarily. None of these is a diagnosis on its own — it's a signal to look at the bigger picture, alongside your liver markers, kidney markers and inflammation (CRP). A high albumin is much less common and almost always simply means dehydration — your blood is a little concentrated, so the value rises. The fix is straightforward: measure again when you're well hydrated. In general, albumin is most useful as a trend: a stable value over time is reassuring, and a meaningful shift is your cue to look closer together with the rest of your results.

Albumin reference ranges

Normal (adults)Reference range for adults; some labs use 35-50 g/L35-55 g/L

Cut-off values differ per lab and method. Albumin is naturally a little lower in older adults, during pregnancy, with oral contraceptive use, and after prolonged bed rest. Always read your own value against the reference range printed on your report.

Educational information only — not medical advice. Consult a healthcare professional for clinical decisions.

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Frequently asked questions

What is a normal albumin level?

In adults, an albumin level of 35-55 g/L is normal (some labs use 35-50 g/L). The boundaries can vary slightly per laboratory and method, so always compare your result with the reference range printed on your report. In older adults, during pregnancy, with oral contraceptive use, and after prolonged bed rest the value is naturally a little lower.

What does a low albumin mean?

An albumin below the lower limit (roughly < 35 g/L) usually points to one of three things: your liver producing less of it, your body losing or using protein faster than you take it in (for example via the kidneys or intestines), or a period of inflammation or illness lowering it temporarily. Undernutrition can play a role too. It is not a diagnosis on its own, but a reason to look at the bigger picture alongside your liver, kidney and inflammation markers (CRP).

What does a high albumin mean?

An albumin above the upper limit (roughly > 55 g/L) is uncommon and almost always simply means dehydration: your blood is a little concentrated, so the value rises. The fix is usually straightforward: measure again when you are well hydrated.

When is an abnormal albumin concerning?

A single value just outside the range is rarely a concern, especially without symptoms. Albumin is most useful as a trend: a stable value over time is reassuring. A clearly and persistently low value, particularly together with abnormal liver or kidney markers or a raised CRP, is a reason to look into it further with a doctor.

Albumin is one of the biomarkers in the Optimize blood test. Book a blood draw at any of 238+ partner labs in the Netherlands, or upload your existing results in the app.

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